Found 4 hits for monomerid = 50437695 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Ubiquitin carboxyl-terminal hydrolase isozyme L1
(Homo sapiens (Human)) | BDBM50437695
(CHEMBL1923233)Show SMILES CCC[C@H](NC(=O)C(=C\c1cccc(Br)n1)\C#N)c1ccccc1 |r| Show InChI InChI=1S/C19H18BrN3O/c1-2-7-17(14-8-4-3-5-9-14)23-19(24)15(13-21)12-16-10-6-11-18(20)22-16/h3-6,8-12,17H,2,7H2,1H3,(H,23,24)/b15-12+/t17-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo University of Agriculture
Curated by ChEMBL
| Assay Description
Inhibition of UCH-L1 in human Z138 cells after 1 hr by immunoblotting analysis |
Bioorg Med Chem Lett 23: 4328-31 (2013)
Article DOI: 10.1016/j.bmcl.2013.05.093
BindingDB Entry DOI: 10.7270/Q2T15528 |
More data for this
Ligand-Target Pair | |
Probable ubiquitin carboxyl-terminal hydrolase FAF-X
(Homo sapiens (Human)) | BDBM50437695
(CHEMBL1923233)Show SMILES CCC[C@H](NC(=O)C(=C\c1cccc(Br)n1)\C#N)c1ccccc1 |r| Show InChI InChI=1S/C19H18BrN3O/c1-2-7-17(14-8-4-3-5-9-14)23-19(24)15(13-21)12-16-10-6-11-18(20)22-16/h3-6,8-12,17H,2,7H2,1H3,(H,23,24)/b15-12+/t17-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant N-terminal His6-Smt3-fusion-tagged Usp9x catalytic domain expressed in Escherichia coli using Ub-AMC as substrate inc... |
Bioorg Med Chem 22: 1450-8 (2014)
Article DOI: 10.1016/j.bmc.2013.12.048
BindingDB Entry DOI: 10.7270/Q2BP0499 |
More data for this
Ligand-Target Pair | |
Ubiquitin carboxyl-terminal hydrolase 5
(Homo sapiens (Human)) | BDBM50437695
(CHEMBL1923233)Show SMILES CCC[C@H](NC(=O)C(=C\c1cccc(Br)n1)\C#N)c1ccccc1 |r| Show InChI InChI=1S/C19H18BrN3O/c1-2-7-17(14-8-4-3-5-9-14)23-19(24)15(13-21)12-16-10-6-11-18(20)22-16/h3-6,8-12,17H,2,7H2,1H3,(H,23,24)/b15-12+/t17-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo University of Agriculture
Curated by ChEMBL
| Assay Description
Inhibition of USP5 in human Z138 cells after 1 hr by immunoblotting analysis |
Bioorg Med Chem Lett 23: 4328-31 (2013)
Article DOI: 10.1016/j.bmcl.2013.05.093
BindingDB Entry DOI: 10.7270/Q2T15528 |
More data for this
Ligand-Target Pair | |
Probable ubiquitin carboxyl-terminal hydrolase FAF-X
(Homo sapiens (Human)) | BDBM50437695
(CHEMBL1923233)Show SMILES CCC[C@H](NC(=O)C(=C\c1cccc(Br)n1)\C#N)c1ccccc1 |r| Show InChI InChI=1S/C19H18BrN3O/c1-2-7-17(14-8-4-3-5-9-14)23-19(24)15(13-21)12-16-10-6-11-18(20)22-16/h3-6,8-12,17H,2,7H2,1H3,(H,23,24)/b15-12+/t17-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo University of Agriculture
Curated by ChEMBL
| Assay Description
Inhibition of USP9x in human Z138 cells after 1 hr by immunoblotting analysis |
Bioorg Med Chem Lett 23: 4328-31 (2013)
Article DOI: 10.1016/j.bmcl.2013.05.093
BindingDB Entry DOI: 10.7270/Q2T15528 |
More data for this
Ligand-Target Pair | |
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