BDBM50437941 CHEMBL1814397
SMILES: CCOC1Oc2ccc(F)cc2C(=O)C1=CNc1cccc(c1)S(N)(=O)=O
InChI Key: InChIKey=VTBRCVNACGXQSS-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ecto-5'-nucleotidase (e5'NT) (Rattus norvegicus (Rat)) | BDBM50437941 (CHEMBL1814397) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 47 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Forman Christian College (A Chartered University) Curated by ChEMBL | Assay Description Inhibition of rat Ecto-5'-nucleotidase transfected in COS7 cells preincubated for 10 mins followed by AMP addition measured after 10 mins | Eur J Med Chem 115: 484-94 (2016) BindingDB Entry DOI: 10.7270/Q2K939D7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Intestinal alkaline phosphatase (IAP) (Bos taurus (Cattle)) | BDBM50437941 (CHEMBL1814397) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.71E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Forman Christian College (A Chartered University) Curated by ChEMBL | Assay Description Inhibition of bovine intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins by spe... | Eur J Med Chem 66: 438-49 (2013) Article DOI: 10.1016/j.ejmech.2013.06.015 BindingDB Entry DOI: 10.7270/Q20K29ZH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tissue non-specific alkaline phosphatase (TNAP) (Bos taurus (Cattle)) | BDBM50437941 (CHEMBL1814397) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Forman Christian College (A Chartered University) Curated by ChEMBL | Assay Description Inhibition of bovine kidney intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins... | Eur J Med Chem 66: 438-49 (2013) Article DOI: 10.1016/j.ejmech.2013.06.015 BindingDB Entry DOI: 10.7270/Q20K29ZH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ecto-5'-nucleotidase (e5'NT) (Rattus norvegicus (Rat)) | BDBM50437941 (CHEMBL1814397) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 990 | n/a | n/a | n/a | n/a | n/a | n/a |
Forman Christian College (A Chartered University) Curated by ChEMBL | Assay Description Inhibition of rat Ecto-5'-nucleotidase transfected in COS7 cells preincubated for 10 mins followed by AMP addition measured after 10 mins | Eur J Med Chem 115: 484-94 (2016) BindingDB Entry DOI: 10.7270/Q2K939D7 | |||||||||||
More data for this Ligand-Target Pair |