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BDBM50437955 CHEMBL2409135

SMILES: Cc1cccc(NC(=O)Nc2cc(CC3CC3)nn2-c2ccccc2)c1

InChI Key: InChIKey=AQQAHAYQAJHXGR-UHFFFAOYSA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50437955   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G protein-activated inward rectifier potassium channel 4


(Homo sapiens)
BDBM50437955
PNG
(CHEMBL2409135)
Show SMILES Cc1cccc(NC(=O)Nc2cc(CC3CC3)nn2-c2ccccc2)c1
Show InChI InChI=1S/C21H22N4O/c1-15-6-5-7-17(12-15)22-21(26)23-20-14-18(13-16-10-11-16)24-25(20)19-8-3-2-4-9-19/h2-9,12,14,16H,10-11,13H2,1H3,(H2,22,23,26)
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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 250n/an/an/an/an/an/a



Northwest Agriculture& Forestry University

Curated by ChEMBL


Assay Description
Inhibition of GIRK1/4 (unknown origin)


Bioorg Med Chem Lett 23: 4562-6 (2013)

More data for this
Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1


(Homo sapiens)
BDBM50437955
PNG
(CHEMBL2409135)
Show SMILES Cc1cccc(NC(=O)Nc2cc(CC3CC3)nn2-c2ccccc2)c1
Show InChI InChI=1S/C21H22N4O/c1-15-6-5-7-17(12-15)22-21(26)23-20-14-18(13-16-10-11-16)24-25(20)19-8-3-2-4-9-19/h2-9,12,14,16H,10-11,13H2,1H3,(H2,22,23,26)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 520n/an/an/an/an/an/a



Northwest Agriculture& Forestry University

Curated by ChEMBL


Assay Description
Inhibition of GIRK1/2 (unknown origin)


Bioorg Med Chem Lett 23: 4562-6 (2013)

More data for this
Ligand-Target Pair