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BDBM50437956 CHEMBL2409126

SMILES: CC(C)c1cc(NC(=O)Nc2ccc(C)cc2)n(n1)-c1ccccc1

InChI Key: InChIKey=GIQDBMXBTVQFQH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50437956   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G protein-activated inward rectifier potassium channel 4


(Homo sapiens (Human))
BDBM50437956
PNG
(CHEMBL2409126)
Show SMILES CC(C)c1cc(NC(=O)Nc2ccc(C)cc2)n(n1)-c1ccccc1
Show InChI InChI=1S/C20H22N4O/c1-14(2)18-13-19(24(23-18)17-7-5-4-6-8-17)22-20(25)21-16-11-9-15(3)10-12-16/h4-14H,1-3H3,(H2,21,22,25)
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UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.80E+3n/an/an/an/an/an/a



Northwest Agriculture& Forestry University

Curated by ChEMBL


Assay Description
Inhibition of GIRK1/4 (unknown origin)


Bioorg Med Chem Lett 23: 4562-6 (2013)


Article DOI: 10.1016/j.bmcl.2013.06.023
BindingDB Entry DOI: 10.7270/Q2R212SN
More data for this
Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1


(Homo sapiens (Human))
BDBM50437956
PNG
(CHEMBL2409126)
Show SMILES CC(C)c1cc(NC(=O)Nc2ccc(C)cc2)n(n1)-c1ccccc1
Show InChI InChI=1S/C20H22N4O/c1-14(2)18-13-19(24(23-18)17-7-5-4-6-8-17)22-20(25)21-16-11-9-15(3)10-12-16/h4-14H,1-3H3,(H2,21,22,25)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.90E+3n/an/an/an/an/an/a



Northwest Agriculture& Forestry University

Curated by ChEMBL


Assay Description
Inhibition of GIRK1/2 (unknown origin)


Bioorg Med Chem Lett 23: 4562-6 (2013)


Article DOI: 10.1016/j.bmcl.2013.06.023
BindingDB Entry DOI: 10.7270/Q2R212SN
More data for this
Ligand-Target Pair