BDBM50437964 CHEMBL2409116
SMILES: Fc1ccc(NC(=O)Nc2cc(nn2-c2ccccc2)C2CCCC2)cc1F
InChI Key: InChIKey=NTHMQZNUIUQADR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50437964 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
G protein-activated inward rectifier potassium channel 4
(Homo sapiens (Human)) | BDBM50437964
(CHEMBL2409116)Show SMILES Fc1ccc(NC(=O)Nc2cc(nn2-c2ccccc2)C2CCCC2)cc1F Show InChI InChI=1S/C21H20F2N4O/c22-17-11-10-15(12-18(17)23)24-21(28)25-20-13-19(14-6-4-5-7-14)26-27(20)16-8-2-1-3-9-16/h1-3,8-14H,4-7H2,(H2,24,25,28) | Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwest Agriculture& Forestry University
Curated by ChEMBL
| Assay Description
Inhibition of GIRK1/4 (unknown origin) |
Bioorg Med Chem Lett 23: 4562-6 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.023
BindingDB Entry DOI: 10.7270/Q2R212SN |
More data for this
Ligand-Target Pair | |
G protein-activated inward rectifier potassium channel 1
(Homo sapiens (Human)) | BDBM50437964
(CHEMBL2409116)Show SMILES Fc1ccc(NC(=O)Nc2cc(nn2-c2ccccc2)C2CCCC2)cc1F Show InChI InChI=1S/C21H20F2N4O/c22-17-11-10-15(12-18(17)23)24-21(28)25-20-13-19(14-6-4-5-7-14)26-27(20)16-8-2-1-3-9-16/h1-3,8-14H,4-7H2,(H2,24,25,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwest Agriculture& Forestry University
Curated by ChEMBL
| Assay Description
Inhibition of GIRK1/2 (unknown origin) |
Bioorg Med Chem Lett 23: 4562-6 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.023
BindingDB Entry DOI: 10.7270/Q2R212SN |
More data for this
Ligand-Target Pair | |
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