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BDBM50437964 CHEMBL2409116

SMILES: Fc1ccc(NC(=O)Nc2cc(nn2-c2ccccc2)C2CCCC2)cc1F

InChI Key: InChIKey=NTHMQZNUIUQADR-UHFFFAOYSA-N

Data: 2 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50437964   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G protein-activated inward rectifier potassium channel 4


(Homo sapiens (Human))
BDBM50437964
PNG
(CHEMBL2409116)
Show SMILES Fc1ccc(NC(=O)Nc2cc(nn2-c2ccccc2)C2CCCC2)cc1F
Show InChI InChI=1S/C21H20F2N4O/c22-17-11-10-15(12-18(17)23)24-21(28)25-20-13-19(14-6-4-5-7-14)26-27(20)16-8-2-1-3-9-16/h1-3,8-14H,4-7H2,(H2,24,25,28)
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.10E+3n/an/an/an/an/an/a



Northwest Agriculture& Forestry University

Curated by ChEMBL


Assay Description
Inhibition of GIRK1/4 (unknown origin)


Bioorg Med Chem Lett 23: 4562-6 (2013)


Article DOI: 10.1016/j.bmcl.2013.06.023
More data for this
Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1


(Homo sapiens (Human))
BDBM50437964
PNG
(CHEMBL2409116)
Show SMILES Fc1ccc(NC(=O)Nc2cc(nn2-c2ccccc2)C2CCCC2)cc1F
Show InChI InChI=1S/C21H20F2N4O/c22-17-11-10-15(12-18(17)23)24-21(28)25-20-13-19(14-6-4-5-7-14)26-27(20)16-8-2-1-3-9-16/h1-3,8-14H,4-7H2,(H2,24,25,28)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.10E+3n/an/an/an/an/an/a



Northwest Agriculture& Forestry University

Curated by ChEMBL


Assay Description
Inhibition of GIRK1/2 (unknown origin)


Bioorg Med Chem Lett 23: 4562-6 (2013)


Article DOI: 10.1016/j.bmcl.2013.06.023
More data for this
Ligand-Target Pair