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BDBM50437966 CHEMBL2409114

SMILES: CC(C)c1cc(NC(=O)Nc2ccc(F)c(F)c2)n(n1)-c1ccccc1

InChI Key: InChIKey=KAVXYMZAMUADJS-UHFFFAOYSA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50437966   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G protein-activated inward rectifier potassium channel 4


(Homo sapiens)
BDBM50437966
PNG
(CHEMBL2409114)
Show SMILES CC(C)c1cc(NC(=O)Nc2ccc(F)c(F)c2)n(n1)-c1ccccc1
Show InChI InChI=1S/C19H18F2N4O/c1-12(2)17-11-18(25(24-17)14-6-4-3-5-7-14)23-19(26)22-13-8-9-15(20)16(21)10-13/h3-12H,1-2H3,(H2,22,23,26)
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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 1.40E+3n/an/an/an/an/an/a



Northwest Agriculture& Forestry University

Curated by ChEMBL


Assay Description
Inhibition of GIRK1/4 (unknown origin)


Bioorg Med Chem Lett 23: 4562-6 (2013)

More data for this
Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1


(Homo sapiens)
BDBM50437966
PNG
(CHEMBL2409114)
Show SMILES CC(C)c1cc(NC(=O)Nc2ccc(F)c(F)c2)n(n1)-c1ccccc1
Show InChI InChI=1S/C19H18F2N4O/c1-12(2)17-11-18(25(24-17)14-6-4-3-5-7-14)23-19(26)22-13-8-9-15(20)16(21)10-13/h3-12H,1-2H3,(H2,22,23,26)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.00E+3n/an/an/an/an/an/a



Northwest Agriculture& Forestry University

Curated by ChEMBL


Assay Description
Inhibition of GIRK1/2 (unknown origin)


Bioorg Med Chem Lett 23: 4562-6 (2013)

More data for this
Ligand-Target Pair