BDBM50437967 CHEMBL2409112

SMILES: Fc1ccc(NC(=O)Nc2cc(nn2-c2ccccc2)-c2ccccc2)cc1F

InChI Key: InChIKey=QTXPHCHEMGIMJO-UHFFFAOYSA-N

Data: 2 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50437967   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-activated inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM50437967 (CHEMBL2409112) Show SMILES Fc1ccc(NC(=O)Nc2cc(nn2-c2ccccc2)-c2ccccc2)cc1F Show InChI InChI=1S/C22H16F2N4O/c23-18-12-11-16(13-19(18)24)25-22(29)26-21-14-20(15-7-3-1-4-8-15)27-28(21)17-9-5-2-6-10-17/h1-14H,(H2,25,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Northwest Agriculture& Forestry University Curated by ChEMBL					Assay Description Inhibition of GIRK1/2 (unknown origin)				Bioorg Med Chem Lett 23: 4562-6 (2013) Article DOI: 10.1016/j.bmcl.2013.06.023 BindingDB Entry DOI: 10.7270/Q2R212SN
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 4 (Homo sapiens (Human))	BDBM50437967 (CHEMBL2409112) Show SMILES Fc1ccc(NC(=O)Nc2cc(nn2-c2ccccc2)-c2ccccc2)cc1F Show InChI InChI=1S/C22H16F2N4O/c23-18-12-11-16(13-19(18)24)25-22(29)26-21-14-20(15-7-3-1-4-8-15)27-28(21)17-9-5-2-6-10-17/h1-14H,(H2,25,26,29)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Northwest Agriculture& Forestry University Curated by ChEMBL					Assay Description Inhibition of GIRK1/4 (unknown origin)				Bioorg Med Chem Lett 23: 4562-6 (2013) Article DOI: 10.1016/j.bmcl.2013.06.023 BindingDB Entry DOI: 10.7270/Q2R212SN
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM50437967 (CHEMBL2409112) Show SMILES Fc1ccc(NC(=O)Nc2cc(nn2-c2ccccc2)-c2ccccc2)cc1F Show InChI InChI=1S/C22H16F2N4O/c23-18-12-11-16(13-19(18)24)25-22(29)26-21-14-20(15-7-3-1-4-8-15)27-28(21)17-9-5-2-6-10-17/h1-14H,(H2,25,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Northwest Agriculture& Forestry University Curated by ChEMBL					Assay Description Activation of GIRK1/2 (unknown origin)				Bioorg Med Chem Lett 23: 4562-6 (2013) Article DOI: 10.1016/j.bmcl.2013.06.023 BindingDB Entry DOI: 10.7270/Q2R212SN
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 4 (Homo sapiens (Human))	BDBM50437967 (CHEMBL2409112) Show SMILES Fc1ccc(NC(=O)Nc2cc(nn2-c2ccccc2)-c2ccccc2)cc1F Show InChI InChI=1S/C22H16F2N4O/c23-18-12-11-16(13-19(18)24)25-22(29)26-21-14-20(15-7-3-1-4-8-15)27-28(21)17-9-5-2-6-10-17/h1-14H,(H2,25,26,29)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
Northwest Agriculture& Forestry University Curated by ChEMBL					Assay Description Activation of GIRK1/4 (unknown origin)				Bioorg Med Chem Lett 23: 4562-6 (2013) Article DOI: 10.1016/j.bmcl.2013.06.023 BindingDB Entry DOI: 10.7270/Q2R212SN
					More data for this Ligand-Target Pair