null

SMILES: CC(C)c1cc(NC(=O)Nc2cccc(c2)C(F)(F)F)n(Cc2ccccc2)n1

InChI Key: InChIKey=YGPDZYXOJUDAIU-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50437968   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-activated inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM50437968 (CHEMBL2409134) Show SMILES CC(C)c1cc(NC(=O)Nc2cccc(c2)C(F)(F)F)n(Cc2ccccc2)n1 Show InChI InChI=1S/C21H21F3N4O/c1-14(2)18-12-19(28(27-18)13-15-7-4-3-5-8-15)26-20(29)25-17-10-6-9-16(11-17)21(22,23)24/h3-12,14H,13H2,1-2H3,(H2,25,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a
Northwest Agriculture& Forestry University Curated by ChEMBL					Assay Description Activation of GIRK1/2 (unknown origin)				Bioorg Med Chem Lett 23: 4562-6 (2013) Article DOI: 10.1016/j.bmcl.2013.06.023 BindingDB Entry DOI: 10.7270/Q2R212SN
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1/4 (Homo sapiens (Human))	BDBM50437968 (CHEMBL2409134) Show SMILES CC(C)c1cc(NC(=O)Nc2cccc(c2)C(F)(F)F)n(Cc2ccccc2)n1 Show InChI InChI=1S/C21H21F3N4O/c1-14(2)18-12-19(28(27-18)13-15-7-4-3-5-8-15)26-20(29)25-17-10-6-9-16(11-17)21(22,23)24/h3-12,14H,13H2,1-2H3,(H2,25,26,29)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a
Northwest Agriculture& Forestry University Curated by ChEMBL					Assay Description Activation of GIRK1/4 (unknown origin)				Bioorg Med Chem Lett 23: 4562-6 (2013) Article DOI: 10.1016/j.bmcl.2013.06.023 BindingDB Entry DOI: 10.7270/Q2R212SN
					More data for this Ligand-Target Pair