BDBM50437970 CHEMBL2409132
SMILES: Fc1ccc(NC(=O)Nc2cc(nn2Cc2ccccc2)C2CC2)cc1Cl
InChI Key: InChIKey=NPMGQKKNNIBVNX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50437970 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
G protein-activated inward rectifier potassium channel 1
(Homo sapiens (Human)) | BDBM50437970
(CHEMBL2409132)Show SMILES Fc1ccc(NC(=O)Nc2cc(nn2Cc2ccccc2)C2CC2)cc1Cl Show InChI InChI=1S/C20H18ClFN4O/c21-16-10-15(8-9-17(16)22)23-20(27)24-19-11-18(14-6-7-14)25-26(19)12-13-4-2-1-3-5-13/h1-5,8-11,14H,6-7,12H2,(H2,23,24,27) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 210 | n/a | n/a | n/a | n/a |
Northwest Agriculture& Forestry University
Curated by ChEMBL
| Assay Description Activation of GIRK1/2 (unknown origin) |
Bioorg Med Chem Lett 23: 4562-6 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.023 BindingDB Entry DOI: 10.7270/Q2R212SN |
More data for this Ligand-Target Pair | |
G protein-activated inward rectifier potassium channel 4
(Homo sapiens (Human)) | BDBM50437970
(CHEMBL2409132)Show SMILES Fc1ccc(NC(=O)Nc2cc(nn2Cc2ccccc2)C2CC2)cc1Cl Show InChI InChI=1S/C20H18ClFN4O/c21-16-10-15(8-9-17(16)22)23-20(27)24-19-11-18(14-6-7-14)25-26(19)12-13-4-2-1-3-5-13/h1-5,8-11,14H,6-7,12H2,(H2,23,24,27) | Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 320 | n/a | n/a | n/a | n/a |
Northwest Agriculture& Forestry University
Curated by ChEMBL
| Assay Description Activation of GIRK1/4 (unknown origin) |
Bioorg Med Chem Lett 23: 4562-6 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.023 BindingDB Entry DOI: 10.7270/Q2R212SN |
More data for this Ligand-Target Pair | |