new BindingDB logo
myBDB logout

BDBM50437972 CHEMBL2409130

SMILES: Cc1ccc(NC(=O)Nc2cc(nn2Cc2ccccc2)C2CC2)cc1

InChI Key: InChIKey=XXUQKPFUJSKBFP-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50437972   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G protein-activated inward rectifier potassium channel 1


(Homo sapiens (Human))
BDBM50437972
PNG
(CHEMBL2409130)
Show SMILES Cc1ccc(NC(=O)Nc2cc(nn2Cc2ccccc2)C2CC2)cc1
Show InChI InChI=1S/C21H22N4O/c1-15-7-11-18(12-8-15)22-21(26)23-20-13-19(17-9-10-17)24-25(20)14-16-5-3-2-4-6-16/h2-8,11-13,17H,9-10,14H2,1H3,(H2,22,23,26)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 570n/an/an/an/a



Northwest Agriculture& Forestry University

Curated by ChEMBL


Assay Description
Activation of GIRK1/2 (unknown origin)


Bioorg Med Chem Lett 23: 4562-6 (2013)


Article DOI: 10.1016/j.bmcl.2013.06.023
BindingDB Entry DOI: 10.7270/Q2R212SN
More data for this
Ligand-Target Pair
G protein-activated inward rectifier potassium channel 4


(Homo sapiens (Human))
BDBM50437972
PNG
(CHEMBL2409130)
Show SMILES Cc1ccc(NC(=O)Nc2cc(nn2Cc2ccccc2)C2CC2)cc1
Show InChI InChI=1S/C21H22N4O/c1-15-7-11-18(12-8-15)22-21(26)23-20-13-19(17-9-10-17)24-25(20)14-16-5-3-2-4-6-16/h2-8,11-13,17H,9-10,14H2,1H3,(H2,22,23,26)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 920n/an/an/an/a



Northwest Agriculture& Forestry University

Curated by ChEMBL


Assay Description
Activation of GIRK1/4 (unknown origin)


Bioorg Med Chem Lett 23: 4562-6 (2013)


Article DOI: 10.1016/j.bmcl.2013.06.023
BindingDB Entry DOI: 10.7270/Q2R212SN
More data for this
Ligand-Target Pair