BDBM50437979 CHEMBL2409110
SMILES: Cc1cc(NC(=O)Nc2ccc(F)c(F)c2)n(Cc2ccccc2)n1
InChI Key: InChIKey=FRKCJYHCVRFZIW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50437979 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
G protein-activated inward rectifier potassium channel 1
(Homo sapiens (Human)) | BDBM50437979
(CHEMBL2409110)Show InChI InChI=1S/C18H16F2N4O/c1-12-9-17(24(23-12)11-13-5-3-2-4-6-13)22-18(25)21-14-7-8-15(19)16(20)10-14/h2-10H,11H2,1H3,(H2,21,22,25) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 70 | n/a | n/a | n/a | n/a |
Northwest Agriculture& Forestry University
Curated by ChEMBL
| Assay Description Activation of GIRK1/2 (unknown origin) |
Bioorg Med Chem Lett 23: 4562-6 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.023 BindingDB Entry DOI: 10.7270/Q2R212SN |
More data for this Ligand-Target Pair | |
G protein-activated inward rectifier potassium channel 4
(Homo sapiens (Human)) | BDBM50437979
(CHEMBL2409110)Show InChI InChI=1S/C18H16F2N4O/c1-12-9-17(24(23-12)11-13-5-3-2-4-6-13)22-18(25)21-14-7-8-15(19)16(20)10-14/h2-10H,11H2,1H3,(H2,21,22,25) | Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 110 | n/a | n/a | n/a | n/a |
Northwest Agriculture& Forestry University
Curated by ChEMBL
| Assay Description Activation of GIRK1/4 (unknown origin) |
Bioorg Med Chem Lett 23: 4562-6 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.023 BindingDB Entry DOI: 10.7270/Q2R212SN |
More data for this Ligand-Target Pair | |