BDBM50437982 CHEMBL2409107
SMILES: Cc1cc(NC(=O)Nc2ccc(F)c(F)c2)n(CC(F)(F)F)n1
InChI Key: InChIKey=XIBSQLDZAQEYFF-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50437982 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
G protein-activated inward rectifier potassium channel 1
(Homo sapiens (Human)) | BDBM50437982
(CHEMBL2409107)Show InChI InChI=1S/C13H11F5N4O/c1-7-4-11(22(21-7)6-13(16,17)18)20-12(23)19-8-2-3-9(14)10(15)5-8/h2-5H,6H2,1H3,(H2,19,20,23) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 460 | n/a | n/a | n/a | n/a |
Northwest Agriculture& Forestry University
Curated by ChEMBL
| Assay Description Activation of GIRK1/2 (unknown origin) |
Bioorg Med Chem Lett 23: 4562-6 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.023 BindingDB Entry DOI: 10.7270/Q2R212SN |
More data for this Ligand-Target Pair | |
G protein-activated inward rectifier potassium channel 4
(Homo sapiens (Human)) | BDBM50437982
(CHEMBL2409107)Show InChI InChI=1S/C13H11F5N4O/c1-7-4-11(22(21-7)6-13(16,17)18)20-12(23)19-8-2-3-9(14)10(15)5-8/h2-5H,6H2,1H3,(H2,19,20,23) | Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a |
Northwest Agriculture& Forestry University
Curated by ChEMBL
| Assay Description Activation of GIRK1/4 (unknown origin) |
Bioorg Med Chem Lett 23: 4562-6 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.023 BindingDB Entry DOI: 10.7270/Q2R212SN |
More data for this Ligand-Target Pair | |