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BDBM50437985 CHEMBL2409104

SMILES: Brc1cccc(NC(=O)Nc2cc(nn2-c2ccccc2)C2CCC2)c1

InChI Key: InChIKey=WMKOFHYQCJBOLA-UHFFFAOYSA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50437985   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G protein-activated inward rectifier potassium channel 1


(Homo sapiens)
BDBM50437985
PNG
(CHEMBL2409104)
Show SMILES Brc1cccc(NC(=O)Nc2cc(nn2-c2ccccc2)C2CCC2)c1
Show InChI InChI=1S/C20H19BrN4O/c21-15-8-5-9-16(12-15)22-20(26)23-19-13-18(14-6-4-7-14)24-25(19)17-10-2-1-3-11-17/h1-3,5,8-14H,4,6-7H2,(H2,22,23,26)
PDB
MMDB

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PC sid
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Similars

Article
PubMed
n/an/a 1.90E+3n/an/an/an/an/an/a



Northwest Agriculture& Forestry University

Curated by ChEMBL


Assay Description
Inhibition of GIRK1/2 (unknown origin)


Bioorg Med Chem Lett 23: 4562-6 (2013)

More data for this
Ligand-Target Pair
G protein-activated inward rectifier potassium channel 4


(Homo sapiens)
BDBM50437985
PNG
(CHEMBL2409104)
Show SMILES Brc1cccc(NC(=O)Nc2cc(nn2-c2ccccc2)C2CCC2)c1
Show InChI InChI=1S/C20H19BrN4O/c21-15-8-5-9-16(12-15)22-20(26)23-19-13-18(14-6-4-7-14)24-25(19)17-10-2-1-3-11-17/h1-3,5,8-14H,4,6-7H2,(H2,22,23,26)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 720n/an/an/an/an/an/a



Northwest Agriculture& Forestry University

Curated by ChEMBL


Assay Description
Inhibition of GIRK1/4 (unknown origin)


Bioorg Med Chem Lett 23: 4562-6 (2013)

More data for this
Ligand-Target Pair