BDBM50438470 CHEMBL2414626

SMILES: Nc1nc2c(CN[C@H](CO)COP(O)(O)=O)c[nH]c2c(=O)[nH]1

InChI Key: InChIKey=GLFXVOLQPODIIY-ZCFIWIBFSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50438470   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (Homo sapiens (Human))	BDBM50438470 (CHEMBL2414626) Show SMILES Nc1nc2c(CN[C@H](CO)COP(O)(O)=O)c[nH]c2c(=O)[nH]1 |r| Show InChI InChI=1S/C10H16N5O6P/c11-10-14-7-5(2-13-8(7)9(17)15-10)1-12-6(3-16)4-21-22(18,19)20/h2,6,12-13,16H,1,3-4H2,(H2,18,19,20)(H3,11,14,15,17)/t6-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Industrial Research Ltd Curated by ChEMBL					Assay Description Inhibition of human HGPRT using xanthine/PRPP assessed as xanthine/guanine conversion to xanthosine-5'-monophosphate/guanosine-5'-monophosphate by sp...				Bioorg Med Chem 21: 5629-46 (2013) Article DOI: 10.1016/j.bmc.2013.02.016 BindingDB Entry DOI: 10.7270/Q2N58NSF
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