BDBM50438476 CHEMBL2414639

SMILES: OC[C@H](CC(F)(F)P(O)(O)=O)NCc1c[nH]c2c1nc[nH]c2=O

InChI Key: InChIKey=OSLYGQAMRJVANH-ZETCQYMHSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50438476   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (Homo sapiens (Human))	BDBM50438476 (CHEMBL2414639) Show SMILES OC[C@H](CC(F)(F)P(O)(O)=O)NCc1c[nH]c2c1nc[nH]c2=O |r| Show InChI InChI=1S/C11H15F2N4O5P/c12-11(13,23(20,21)22)1-7(4-18)14-2-6-3-15-9-8(6)16-5-17-10(9)19/h3,5,7,14-15,18H,1-2,4H2,(H,16,17,19)(H2,20,21,22)/t7-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Industrial Research Ltd Curated by ChEMBL					Assay Description Inhibition of human HGPRT using xanthine/PRPP assessed as xanthine/guanine conversion to xanthosine-5'-monophosphate/guanosine-5'-monophosphate by sp...				Bioorg Med Chem 21: 5629-46 (2013) Article DOI: 10.1016/j.bmc.2013.02.016 BindingDB Entry DOI: 10.7270/Q2N58NSF
					More data for this Ligand-Target Pair