BDBM50439012 CHEMBL2420812

SMILES: CCNC(=O)Nc1cc(NC(=O)c2c(Cl)cccc2Cl)ccn1

InChI Key: InChIKey=SHWAYLFZFJFUFD-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50439012   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50439012 (CHEMBL2420812) Show SMILES CCNC(=O)Nc1cc(NC(=O)c2c(Cl)cccc2Cl)ccn1 Show InChI InChI=1S/C15H14Cl2N4O2/c1-2-18-15(23)21-12-8-9(6-7-19-12)20-14(22)13-10(16)4-3-5-11(13)17/h3-8H,2H2,1H3,(H3,18,19,20,21,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50439012 (CHEMBL2420812) Show SMILES CCNC(=O)Nc1cc(NC(=O)c2c(Cl)cccc2Cl)ccn1 Show InChI InChI=1S/C15H14Cl2N4O2/c1-2-18-15(23)21-12-8-9(6-7-19-12)20-14(22)13-10(16)4-3-5-11(13)17/h3-8H,2H2,1H3,(H3,18,19,20,21,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of JAK1 (unknown origin)				Eur J Med Chem 67: 175-87 (2013) Article DOI: 10.1016/j.ejmech.2013.03.070 BindingDB Entry DOI: 10.7270/Q2416ZGB
					More data for this Ligand-Target Pair