BDBM50439403 CHEMBL1558022

SMILES: CN(C)S(=O)(=O)c1cc(NC(=O)Cc2ccccc2Cl)ccc1C

InChI Key: InChIKey=PFJHWSKYOAMNAS-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50439403   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-activated inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM50439403 (CHEMBL1558022) Show SMILES CN(C)S(=O)(=O)c1cc(NC(=O)Cc2ccccc2Cl)ccc1C Show InChI InChI=1S/C17H19ClN2O3S/c1-12-8-9-14(11-16(12)24(22,23)20(2)3)19-17(21)10-13-6-4-5-7-15(13)18/h4-9,11H,10H2,1-3H3,(H,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/2 (unknown origin) by cell-based thallium flux assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 4 (Homo sapiens (Human))	BDBM50439403 (CHEMBL1558022) Show SMILES CN(C)S(=O)(=O)c1cc(NC(=O)Cc2ccccc2Cl)ccc1C Show InChI InChI=1S/C17H19ClN2O3S/c1-12-8-9-14(11-16(12)24(22,23)20(2)3)19-17(21)10-13-6-4-5-7-15(13)18/h4-9,11H,10H2,1-3H3,(H,19,21)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Activation of GIRK1/4 (unknown origin) by cell-based thallium flux assay				Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1
					More data for this Ligand-Target Pair