BindingDB logo
myBDB logout

BDBM50439407 CHEMBL2420535

SMILES: FC(F)(F)c1ccc(NC(=O)Cc2ccccc2Cl)cc1

InChI Key: InChIKey=HTHVHCRUUPPVKH-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50439407   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G protein-activated inward rectifier potassium channel 1


(Homo sapiens (Human))
BDBM50439407
PNG
(CHEMBL2420535)
Show SMILES FC(F)(F)c1ccc(NC(=O)Cc2ccccc2Cl)cc1
Show InChI InChI=1S/C15H11ClF3NO/c16-13-4-2-1-3-10(13)9-14(21)20-12-7-5-11(6-8-12)15(17,18)19/h1-8H,9H2,(H,20,21)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



Vanderbilt University

Curated by ChEMBL


Assay Description
Activation of GIRK1/2 (unknown origin) transfected in HEK293 cells after 4 mins by thallium flux-based fluorescence assay


Bioorg Med Chem Lett 23: 5195-8 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.002
More data for this
Ligand-Target Pair
G protein-activated inward rectifier potassium channel 4


(Homo sapiens (Human))
BDBM50439407
PNG
(CHEMBL2420535)
Show SMILES FC(F)(F)c1ccc(NC(=O)Cc2ccccc2Cl)cc1
Show InChI InChI=1S/C15H11ClF3NO/c16-13-4-2-1-3-10(13)9-14(21)20-12-7-5-11(6-8-12)15(17,18)19/h1-8H,9H2,(H,20,21)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 2.10E+3n/an/an/an/a



Vanderbilt University

Curated by ChEMBL


Assay Description
Activation of GIRK1/4 (unknown origin) transfected in HEK293 cells after 4 mins by thallium flux-based fluorescence assay


Bioorg Med Chem Lett 23: 5195-8 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.002
More data for this
Ligand-Target Pair