BDBM50439434 CHEMBL2420701

SMILES: Cn1cc(c(n1)-c1ccc(F)cc1)-c1ccnc(CO)c1

InChI Key: InChIKey=HRZWHDGMDXCUTR-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50439434   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase I isoform delta (Homo sapiens (Human))	BDBM50439434 (CHEMBL2420701) Show SMILES Cn1cc(c(n1)-c1ccc(F)cc1)-c1ccnc(CO)c1 Show InChI InChI=1S/C16H14FN3O/c1-20-9-15(12-6-7-18-14(8-12)10-21)16(19-20)11-2-4-13(17)5-3-11/h2-9,21H,10H2,1H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	237	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human CK1 delta transfected in african green monkey cos7 cells after overnight incubation by whole cell assay				J Med Chem 56: 6819-28 (2013) Article DOI: 10.1021/jm4006324 BindingDB Entry DOI: 10.7270/Q2125V36
					More data for this Ligand-Target Pair
Casein kinase I isoform delta (Homo sapiens (Human))	BDBM50439434 (CHEMBL2420701) Show SMILES Cn1cc(c(n1)-c1ccc(F)cc1)-c1ccnc(CO)c1 Show InChI InChI=1S/C16H14FN3O/c1-20-9-15(12-6-7-18-14(8-12)10-21)16(19-20)11-2-4-13(17)5-3-11/h2-9,21H,10H2,1H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of CK1 delta (unknown origin) using PLSRTLpSVASLPGL as substrate after 60 mins by microplate reader analysis				J Med Chem 56: 6819-28 (2013) Article DOI: 10.1021/jm4006324 BindingDB Entry DOI: 10.7270/Q2125V36
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50439434 (CHEMBL2420701) Show SMILES Cn1cc(c(n1)-c1ccc(F)cc1)-c1ccnc(CO)c1 Show InChI InChI=1S/C16H14FN3O/c1-20-9-15(12-6-7-18-14(8-12)10-21)16(19-20)11-2-4-13(17)5-3-11/h2-9,21H,10H2,1H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of CK1 epsilon (unknown origin) using PLSRTLpSVASLPGL as substrate after 85 mins by microplate reader analysis				J Med Chem 56: 6819-28 (2013) Article DOI: 10.1021/jm4006324 BindingDB Entry DOI: 10.7270/Q2125V36
					More data for this Ligand-Target Pair