BDBM50440054 CHEMBL2426103

SMILES: OC(=O)CCC(=O)N1N=C(CC1c1ccc(Cl)cc1)c1c(-c2ccc(cc2)C#N)c2ccccc2[nH]c1=O

InChI Key: InChIKey=NVWFIRBAVZQFJX-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50440054   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 2D (Rattus norvegicus (Rat))	BDBM50440054 (CHEMBL2426103) Show SMILES OC(=O)CCC(=O)N1N=C(CC1c1ccc(Cl)cc1)c1c(-c2ccc(cc2)C#N)c2ccccc2[nH]c1=O |c:8| Show InChI InChI=1S/C29H21ClN4O4/c30-20-11-9-18(10-12-20)24-15-23(33-34(24)25(35)13-14-26(36)37)28-27(19-7-5-17(16-31)6-8-19)21-3-1-2-4-22(21)32-29(28)38/h1-12,24H,13-15H2,(H,32,38)(H,36,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp method				J Med Chem 56: 6434-56 (2013) Article DOI: 10.1021/jm400652r BindingDB Entry DOI: 10.7270/Q26H4JTJ
					More data for this Ligand-Target Pair
NMDA receptor subunit N2A (GluN2A) (Rattus norvegicus (Rat))	BDBM50440054 (CHEMBL2426103) Show SMILES OC(=O)CCC(=O)N1N=C(CC1c1ccc(Cl)cc1)c1c(-c2ccc(cc2)C#N)c2ccccc2[nH]c1=O |c:8| Show InChI InChI=1S/C29H21ClN4O4/c30-20-11-9-18(10-12-20)24-15-23(33-34(24)25(35)13-14-26(36)37)28-27(19-7-5-17(16-31)6-8-19)21-3-1-2-4-22(21)32-29(28)38/h1-12,24H,13-15H2,(H,32,38)(H,36,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.56E+5	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Negative allosteric modulation of recombinant rat GluN2A receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp method				J Med Chem 56: 6434-56 (2013) Article DOI: 10.1021/jm400652r BindingDB Entry DOI: 10.7270/Q26H4JTJ
					More data for this Ligand-Target Pair
NMDA receptor subunit 2C (GluN2C) (Rattus norvegicus (Rat))	BDBM50440054 (CHEMBL2426103) Show SMILES OC(=O)CCC(=O)N1N=C(CC1c1ccc(Cl)cc1)c1c(-c2ccc(cc2)C#N)c2ccccc2[nH]c1=O |c:8| Show InChI InChI=1S/C29H21ClN4O4/c30-20-11-9-18(10-12-20)24-15-23(33-34(24)25(35)13-14-26(36)37)28-27(19-7-5-17(16-31)6-8-19)21-3-1-2-4-22(21)32-29(28)38/h1-12,24H,13-15H2,(H,32,38)(H,36,37)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Negative allosteric modulation of recombinant rat GluN2C receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp method				J Med Chem 56: 6434-56 (2013) Article DOI: 10.1021/jm400652r BindingDB Entry DOI: 10.7270/Q26H4JTJ
					More data for this Ligand-Target Pair