BDBM50440066 CHEMBL2426074

SMILES: COC(=O)C=CC(=O)N1N=C(CC1c1ccc(Cl)cc1)c1c(-c2ccc(Br)cc2)c2ccccc2[nH]c1=O

InChI Key: InChIKey=NJLVSCUZHDWYHC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50440066   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NMDA receptor subunit 2C (GluN2C) (Rattus norvegicus (Rat))	BDBM50440066 (CHEMBL2426074) Show SMILES COC(=O)C=CC(=O)N1N=C(CC1c1ccc(Cl)cc1)c1c(-c2ccc(Br)cc2)c2ccccc2[nH]c1=O |w:4.3,c:9| Show InChI InChI=1S/C29H21BrClN3O4/c1-38-26(36)15-14-25(35)34-24(17-8-12-20(31)13-9-17)16-23(33-34)28-27(18-6-10-19(30)11-7-18)21-4-2-3-5-22(21)32-29(28)37/h2-15,24H,16H2,1H3,(H,32,37)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Negative allosteric modulation of recombinant rat GluN2C receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp method				J Med Chem 56: 6434-56 (2013) Article DOI: 10.1021/jm400652r BindingDB Entry DOI: 10.7270/Q26H4JTJ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2D (Rattus norvegicus (Rat))	BDBM50440066 (CHEMBL2426074) Show SMILES COC(=O)C=CC(=O)N1N=C(CC1c1ccc(Cl)cc1)c1c(-c2ccc(Br)cc2)c2ccccc2[nH]c1=O |w:4.3,c:9| Show InChI InChI=1S/C29H21BrClN3O4/c1-38-26(36)15-14-25(35)34-24(17-8-12-20(31)13-9-17)16-23(33-34)28-27(18-6-10-19(30)11-7-18)21-4-2-3-5-22(21)32-29(28)37/h2-15,24H,16H2,1H3,(H,32,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp method				J Med Chem 56: 6434-56 (2013) Article DOI: 10.1021/jm400652r BindingDB Entry DOI: 10.7270/Q26H4JTJ
					More data for this Ligand-Target Pair