BDBM50440072 CHEMBL2426067
SMILES: OC(=O)CCC(=O)N1N=C(CC1c1ccc(Cl)cc1)c1c(-c2cc(Cl)cc(Cl)c2)c2ccccc2[nH]c1=O
InChI Key: InChIKey=GUTCFCHIXFDARD-UHFFFAOYSA-N
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutamate receptor ionotropic, NMDA 2D (Rattus norvegicus (Rat)) | BDBM50440072 (CHEMBL2426067) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Curated by ChEMBL | Assay Description Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp method | J Med Chem 56: 6434-56 (2013) Article DOI: 10.1021/jm400652r BindingDB Entry DOI: 10.7270/Q26H4JTJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NMDA receptor subunit N2A (GluN2A) (Rattus norvegicus (Rat)) | BDBM50440072 (CHEMBL2426067) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Curated by ChEMBL | Assay Description Negative allosteric modulation of recombinant rat GluN2A receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp method | J Med Chem 56: 6434-56 (2013) Article DOI: 10.1021/jm400652r BindingDB Entry DOI: 10.7270/Q26H4JTJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat)) | BDBM50440072 (CHEMBL2426067) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Curated by ChEMBL | Assay Description Negative allosteric modulation of recombinant rat GluN2B receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp method | J Med Chem 56: 6434-56 (2013) Article DOI: 10.1021/jm400652r BindingDB Entry DOI: 10.7270/Q26H4JTJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NMDA receptor subunit 2C (GluN2C) (Rattus norvegicus (Rat)) | BDBM50440072 (CHEMBL2426067) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 780 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Curated by ChEMBL | Assay Description Negative allosteric modulation of recombinant rat GluN2C receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp method | J Med Chem 56: 6434-56 (2013) Article DOI: 10.1021/jm400652r BindingDB Entry DOI: 10.7270/Q26H4JTJ | |||||||||||
More data for this Ligand-Target Pair |