BDBM50440087 CHEMBL2426090

SMILES: CN(C)c1ccc(cc1)C1CC(=NN1C(=O)CCC(O)=O)c1c(-c2ccccc2)c2cc(Cl)ccc2[nH]c1=O

InChI Key: InChIKey=OLORPKYJFYZVRR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50440087   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NMDA receptor subunit 2C (GluN2C) (Rattus norvegicus (Rat))	BDBM50440087 (CHEMBL2426090) Show SMILES CN(C)c1ccc(cc1)C1CC(=NN1C(=O)CCC(O)=O)c1c(-c2ccccc2)c2cc(Cl)ccc2[nH]c1=O |c:12| Show InChI InChI=1S/C30H27ClN4O4/c1-34(2)21-11-8-18(9-12-21)25-17-24(33-35(25)26(36)14-15-27(37)38)29-28(19-6-4-3-5-7-19)22-16-20(31)10-13-23(22)32-30(29)39/h3-13,16,25H,14-15,17H2,1-2H3,(H,32,39)(H,37,38)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Negative allosteric modulation of recombinant rat GluN2C receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp method				J Med Chem 56: 6434-56 (2013) Article DOI: 10.1021/jm400652r BindingDB Entry DOI: 10.7270/Q26H4JTJ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2D (Rattus norvegicus (Rat))	BDBM50440087 (CHEMBL2426090) Show SMILES CN(C)c1ccc(cc1)C1CC(=NN1C(=O)CCC(O)=O)c1c(-c2ccccc2)c2cc(Cl)ccc2[nH]c1=O |c:12| Show InChI InChI=1S/C30H27ClN4O4/c1-34(2)21-11-8-18(9-12-21)25-17-24(33-35(25)26(36)14-15-27(37)38)29-28(19-6-4-3-5-7-19)22-16-20(31)10-13-23(22)32-30(29)39/h3-13,16,25H,14-15,17H2,1-2H3,(H,32,39)(H,37,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp method				J Med Chem 56: 6434-56 (2013) Article DOI: 10.1021/jm400652r BindingDB Entry DOI: 10.7270/Q26H4JTJ
					More data for this Ligand-Target Pair