BDBM50440153 CHEMBL2426460

SMILES: CCc1sc(nc1CSc1nc(N)cc(N)n1)-c1ccc(F)cc1

InChI Key: InChIKey=DJZCMFDRMBCUHE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50440153   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Deoxycytidine kinase (Homo sapiens (Human))	BDBM50440153 (CHEMBL2426460) Show SMILES CCc1sc(nc1CSc1nc(N)cc(N)n1)-c1ccc(F)cc1 Show InChI InChI=1S/C16H16FN5S2/c1-2-12-11(8-23-16-21-13(18)7-14(19)22-16)20-15(24-12)9-3-5-10(17)6-4-9/h3-7H,2,8H2,1H3,(H4,18,19,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
California NanoSystems Institute Curated by ChEMBL					Assay Description Inhibition of dCK in human CCRF-CEM cells assessed as inhibition of tritiated deoxycytidine [3H]-dC uptake				J Med Chem 56: 6696-708 (2013) Article DOI: 10.1021/jm400457y BindingDB Entry DOI: 10.7270/Q2JS9RWP
					More data for this Ligand-Target Pair
Deoxycytidine kinase (Mus musculus)	BDBM50440153 (CHEMBL2426460) Show SMILES CCc1sc(nc1CSc1nc(N)cc(N)n1)-c1ccc(F)cc1 Show InChI InChI=1S/C16H16FN5S2/c1-2-12-11(8-23-16-21-13(18)7-14(19)22-16)20-15(24-12)9-3-5-10(17)6-4-9/h3-7H,2,8H2,1H3,(H4,18,19,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	265	n/a	n/a	n/a	n/a	n/a	n/a
California NanoSystems Institute Curated by ChEMBL					Assay Description Inhibition of dCK in mouse L1210 cells assessed as inhibition of tritiated deoxycytidine [3H]-dC uptake				J Med Chem 56: 6696-708 (2013) Article DOI: 10.1021/jm400457y BindingDB Entry DOI: 10.7270/Q2JS9RWP
					More data for this Ligand-Target Pair