BDBM50440154 CHEMBL2426459

SMILES: CCc1sc(nc1CSc1nc(N)cc(N)n1)-c1cc(F)cc(F)c1

InChI Key: InChIKey=HGTYIESKNDANJV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50440154   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Deoxycytidine kinase (Homo sapiens (Human))	BDBM50440154 (CHEMBL2426459) Show SMILES CCc1sc(nc1CSc1nc(N)cc(N)n1)-c1cc(F)cc(F)c1 Show InChI InChI=1S/C16H15F2N5S2/c1-2-12-11(7-24-16-22-13(19)6-14(20)23-16)21-15(25-12)8-3-9(17)5-10(18)4-8/h3-6H,2,7H2,1H3,(H4,19,20,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	162	n/a	n/a	n/a	n/a	n/a	n/a
California NanoSystems Institute Curated by ChEMBL					Assay Description Inhibition of dCK in human CCRF-CEM cells assessed as inhibition of tritiated deoxycytidine [3H]-dC uptake				J Med Chem 56: 6696-708 (2013) Article DOI: 10.1021/jm400457y BindingDB Entry DOI: 10.7270/Q2JS9RWP
					More data for this Ligand-Target Pair
Deoxycytidine kinase (Mus musculus)	BDBM50440154 (CHEMBL2426459) Show SMILES CCc1sc(nc1CSc1nc(N)cc(N)n1)-c1cc(F)cc(F)c1 Show InChI InChI=1S/C16H15F2N5S2/c1-2-12-11(7-24-16-22-13(19)6-14(20)23-16)21-15(25-12)8-3-9(17)5-10(18)4-8/h3-6H,2,7H2,1H3,(H4,19,20,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
California NanoSystems Institute Curated by ChEMBL					Assay Description Inhibition of dCK in mouse L1210 cells assessed as inhibition of tritiated deoxycytidine [3H]-dC uptake				J Med Chem 56: 6696-708 (2013) Article DOI: 10.1021/jm400457y BindingDB Entry DOI: 10.7270/Q2JS9RWP
					More data for this Ligand-Target Pair