BDBM50440256 CHEMBL2426668

SMILES: COCC(N1CC2(C1)CCN(CC2)C(=O)Cc1ccc(OC)cn1)c1ccc(cc1)-c1ncccn1

InChI Key: InChIKey=RPUPHHMLWAERGS-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50440256   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ghrelin receptor (Homo sapiens (Human))	BDBM50440256 (CHEMBL2426668) Show SMILES COCC(N1CC2(C1)CCN(CC2)C(=O)Cc1ccc(OC)cn1)c1ccc(cc1)-c1ncccn1 Show InChI InChI=1S/C28H33N5O3/c1-35-18-25(21-4-6-22(7-5-21)27-29-12-3-13-30-27)33-19-28(20-33)10-14-32(15-11-28)26(34)16-23-8-9-24(36-2)17-31-23/h3-9,12-13,17,25H,10-11,14-16,18-20H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.63E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [125I]-ghrelin from human GHS-R1a expressed in tetracycline inducible HEK293 cells after 8 hrs by liquid scintillation counting				Bioorg Med Chem Lett 23: 5410-4 (2013) Article DOI: 10.1016/j.bmcl.2013.07.044 BindingDB Entry DOI: 10.7270/Q25H7HP5
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50440256 (CHEMBL2426668) Show SMILES COCC(N1CC2(C1)CCN(CC2)C(=O)Cc1ccc(OC)cn1)c1ccc(cc1)-c1ncccn1 Show InChI InChI=1S/C28H33N5O3/c1-35-18-25(21-4-6-22(7-5-21)27-29-12-3-13-30-27)33-19-28(20-33)10-14-32(15-11-28)26(34)16-23-8-9-24(36-2)17-31-23/h3-9,12-13,17,25H,10-11,14-16,18-20H2,1-2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.08E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of N-methyl [3H]-scopolamine from recombinant human muscarinic acetylcholine receptor M2 expressed in CHO cells after 2 hrs by liquid sc...				Bioorg Med Chem Lett 23: 5410-4 (2013) Article DOI: 10.1016/j.bmcl.2013.07.044 BindingDB Entry DOI: 10.7270/Q25H7HP5
					More data for this Ligand-Target Pair