BDBM50440258 CHEMBL2426670
SMILES: COc1ccc(CC(=O)N2CCC3(CN(C3)[C@H](C)c3ccc(cc3)-c3ncccn3)CC2)nc1
InChI Key: InChIKey=OBWXZZBFWOHLCS-HXUWFJFHSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human)) | BDBM50440258 (CHEMBL2426670) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Displacement of N-methyl [3H]-scopolamine from recombinant human muscarinic acetylcholine receptor M2 expressed in CHO cells after 2 hrs by liquid sc... | Bioorg Med Chem Lett 23: 5410-4 (2013) Article DOI: 10.1016/j.bmcl.2013.07.044 BindingDB Entry DOI: 10.7270/Q25H7HP5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ghrelin receptor (Homo sapiens (Human)) | BDBM50440258 (CHEMBL2426670) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.51E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Displacement of [125I]-ghrelin from human GHS-R1a expressed in tetracycline inducible HEK293 cells after 8 hrs by liquid scintillation counting | Bioorg Med Chem Lett 23: 5410-4 (2013) Article DOI: 10.1016/j.bmcl.2013.07.044 BindingDB Entry DOI: 10.7270/Q25H7HP5 | |||||||||||
More data for this Ligand-Target Pair |