BDBM50440270 CHEMBL215432
SMILES: COc1ccc(\C=C\c2ccc(O)c(O)c2)cc1
InChI Key: InChIKey=TVQUCCIFVFNBAV-NSCUHMNNSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ribosyldihydronicotinamide dehydrogenase [quinone] (Homo sapiens (Human)) | BDBM50440270 (CHEMBL215432) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of human quinone reductase 2 expressed in Escherichia coli BL21(DE3) using N-methyldihydronicotinamide as co-substrate | Bioorg Med Chem 21: 6022-37 (2013) Article DOI: 10.1016/j.bmc.2013.07.037 BindingDB Entry DOI: 10.7270/Q21R6RX0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear factor NF-kappa-B (Homo sapiens (Human)) | BDBM50440270 (CHEMBL215432) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
STC.UNM US Patent | Assay Description The actual target(s) whereby the most active substituted trans-stilbenes inhibit the TNFα-induced activation of NF-κB remains to be identif... | US Patent US8980954 (2015) BindingDB Entry DOI: 10.7270/Q27D2SWV | |||||||||||
More data for this Ligand-Target Pair |