BDBM50440280 CHEMBL489688

SMILES: COc1ccc(\C=C(\c2cccc(c2)C(F)(F)F)C(F)(F)F)cc1OC

InChI Key: InChIKey=ULPHPESRRSVYRJ-ZSOIEALJSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50440280   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribosyldihydronicotinamide dehydrogenase [quinone] (Homo sapiens (Human))	BDBM50440280 (CHEMBL489688) Show SMILES COc1ccc(\C=C(\c2cccc(c2)C(F)(F)F)C(F)(F)F)cc1OC Show InChI InChI=1S/C18H14F6O2/c1-25-15-7-6-11(9-16(15)26-2)8-14(18(22,23)24)12-4-3-5-13(10-12)17(19,20)21/h3-10H,1-2H3/b14-8-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibition of human quinone reductase 2 expressed in Escherichia coli BL21(DE3) using N-methyldihydronicotinamide as co-substrate				Bioorg Med Chem 21: 6022-37 (2013) Article DOI: 10.1016/j.bmc.2013.07.037 BindingDB Entry DOI: 10.7270/Q21R6RX0
					More data for this Ligand-Target Pair