BDBM50440514 CHEMBL2426190
SMILES: Clc1ccc(NC(=O)Nc2nnc(s2)-c2ccncc2)cc1C#N
InChI Key: InChIKey=VNTLJDTUZPBYMW-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Werner syndrome ATP-dependent helicase (Homo sapiens (Human)) | BDBM50440514 (CHEMBL2426190) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of WRN (unknown origin) by gel-based DNA unwinding assay | Bioorg Med Chem Lett 23: 5660-6 (2013) Checked by Author Article DOI: 10.1016/j.bmcl.2013.08.025 BindingDB Entry DOI: 10.7270/Q2KK9D78 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bloom syndrome protein (Homo sapiens (Human)) | BDBM50440514 (CHEMBL2426190) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of BLM (unknown origin) by gel-based DNA unwinding assay | Bioorg Med Chem Lett 23: 5660-6 (2013) Checked by Author Article DOI: 10.1016/j.bmcl.2013.08.025 BindingDB Entry DOI: 10.7270/Q2KK9D78 | |||||||||||
More data for this Ligand-Target Pair |