BDBM50440528 CHEMBL2426165
SMILES: Brc1cc(NC(=O)Nc2nnc(s2)-c2ccncc2)ccc1C#N
InChI Key: InChIKey=ASFRMDYKXVUOOC-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Bloom syndrome protein (Homo sapiens (Human)) | BDBM50440528 (CHEMBL2426165) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 910 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of BLM (unknown origin) by gel-based DNA unwinding assay | Bioorg Med Chem Lett 23: 5660-6 (2013) Checked by Author Article DOI: 10.1016/j.bmcl.2013.08.025 BindingDB Entry DOI: 10.7270/Q2KK9D78 | |||||||||||
More data for this Ligand-Target Pair |