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SMILES: CC(C)[C@@]1(CC[C@H](C1)NCc1ccccc1)C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=XOXUVAJFNVIHLG-GGAORHGYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50440542   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-C motif chemokine 2


(Homo sapiens (Human))		BDBM50440542
PNG
(CHEMBL2426342)
Show SMILES CC(C)[C@@]1(CC[C@H](C1)NCc1ccccc1)C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F |r|
Show InChI InChI=1S/C25H28F6N2O/c1-16(2)23(9-8-21(13-23)32-14-17-6-4-3-5-7-17)22(34)33-15-18-10-19(24(26,27)28)12-20(11-18)25(29,30)31/h3-7,10-12,16,21,32H,8-9,13-15H2,1-2H3,(H,33,34)/t21-,23+/m1/s1
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Article
PubMed
 437n/an/an/an/an/an/an/an/a



Leiden University

Curated by ChEMBL


Assay Description
Displacement of [125I]-CCL2 from human CCR2 receptor expressed in human U2OS cell membranes

J Med Chem 56: 7706-14 (2013)


Article DOI: 10.1021/jm4011737
BindingDB Entry DOI: 10.7270/Q2FT8NG3
More data for this
Ligand-Target Pair