BDBM50440626 CHEMBL2426548
SMILES: Cc1cc(=O)oc2cc(Oc3ccc(Cl)cc3O)ccc12
InChI Key: InChIKey=XXMITAGGDYBPQV-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
3-oxoacyl-(Acyl-carrier protein) reductase (Plasmodium falciparum (isolate 3D7)) | BDBM50440626 (CHEMBL2426548) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bologna Curated by ChEMBL | Assay Description Inhibition of recombinant Plasmodium falciparum 3D7 FabG using acetoacetyl-CoA as substrate after 10 mins in presence of NADPH | J Med Chem 56: 7516-26 (2013) Article DOI: 10.1021/jm400637m BindingDB Entry DOI: 10.7270/Q26D5VD7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty acid synthase (Plasmodium falciparum) | BDBM50440626 (CHEMBL2426548) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bologna Curated by ChEMBL | Assay Description Inhibition of recombinant Plasmodium falciparum FabZ using crotonoyl-CoA as substrate after 10 mins | J Med Chem 56: 7516-26 (2013) Article DOI: 10.1021/jm400637m BindingDB Entry DOI: 10.7270/Q26D5VD7 | |||||||||||
More data for this Ligand-Target Pair |