null
SMILES: CC(C)Nc1ccc2nnc([C@@H](C)c3c[nH]c4ncccc34)n2n1
InChI Key: InChIKey=PUIUZHJXBDSQEZ-NSHDSACASA-N
PDB links: 1 PDB ID matches this monomer.
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM50440884 (CHEMBL2431816) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of N-terminal His-6-tagged human recombinant c-Met (974 to 1390) using Ac-ARDMYDKEYYSVHNK as substrate by spectrophotometric assay | J Med Chem 56: 6651-65 (2013) Article DOI: 10.1021/jm400926x BindingDB Entry DOI: 10.7270/Q2HM59WR | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM50440884 (CHEMBL2431816) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of c-Met autophosphorylation in human A549 cells after 1 hr by ELISA | J Med Chem 56: 6651-65 (2013) Article DOI: 10.1021/jm400926x BindingDB Entry DOI: 10.7270/Q2HM59WR | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |