BDBM50440909 CHEMBL2431907

SMILES: CC(C)(C)C(=O)N1Cc2ccc(cc2C1)C(=O)NO

InChI Key: InChIKey=HMJYQUAVTIECII-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50440909   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 3 (Homo sapiens (Human))	BDBM50440909 (CHEMBL2431907) Show SMILES CC(C)(C)C(=O)N1Cc2ccc(cc2C1)C(=O)NO Show InChI InChI=1S/C14H18N2O3/c1-14(2,3)13(18)16-7-10-5-4-9(12(17)15-19)6-11(10)8-16/h4-6,19H,7-8H2,1-3H3,(H,15,17)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of full length C-terminal His6x-tagged recombinant human HDAC3 expressed in baculovirus using Arg-His-Lys-Lys (Ac) as substrate after 1 hr...				J Med Chem 56: 7201-11 (2013) Article DOI: 10.1021/jm400385r BindingDB Entry DOI: 10.7270/Q2862HX7
					More data for this Ligand-Target Pair