BDBM50441060 CHEMBL2430251

SMILES: Cc1[nH]c2c(CCC\C2=C2\C(=O)Nc3ccc(F)cc23)c1C(=O)N1CCOCC1

InChI Key: InChIKey=IVQYCPCHHYNLKB-CYVLTUHYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50441060   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50441060 (CHEMBL2430251) Show SMILES Cc1[nH]c2c(CCC\C2=C2\C(=O)Nc3ccc(F)cc23)c1C(=O)N1CCOCC1 Show InChI InChI=1S/C22H22FN3O3/c1-12-18(22(28)26-7-9-29-10-8-26)14-3-2-4-15(20(14)24-12)19-16-11-13(23)5-6-17(16)25-21(19)27/h5-6,11,24H,2-4,7-10H2,1H3,(H,25,27)/b19-15-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University of Technology Curated by ChEMBL					Assay Description Inhibition of PDGFR-beta (unknown origin)				Bioorg Med Chem Lett 23: 5630-3 (2013) Article DOI: 10.1016/j.bmcl.2013.08.037 BindingDB Entry DOI: 10.7270/Q23F4R30
					More data for this Ligand-Target Pair