BDBM50441166 CHEMBL2430875

SMILES: COc1ccc-2c(c1)C(=N[C@@H](CC(=O)Nc1ccc(F)cc1)c1nnc(C)n-21)c1ccc(Cl)cc1

InChI Key: InChIKey=MHBAKXUSLHCRMN-QFIPXVFZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50441166   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50441166 (CHEMBL2430875) Show SMILES COc1ccc-2c(c1)C(=N[C@@H](CC(=O)Nc1ccc(F)cc1)c1nnc(C)n-21)c1ccc(Cl)cc1 |r,c:9| Show InChI InChI=1S/C26H21ClFN5O2/c1-15-31-32-26-22(14-24(34)29-19-9-7-18(28)8-10-19)30-25(16-3-5-17(27)6-4-16)21-13-20(35-2)11-12-23(21)33(15)26/h3-13,22H,14H2,1-2H3,(H,29,34)/t22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Binding affinity to His6-tagged BRD4 (unknown origin) after 60 mins by fluorescence anisotropy binding Assay				J Med Chem 56: 7501-15 (2013) Article DOI: 10.1021/jm401088k BindingDB Entry DOI: 10.7270/Q2SX6FN7
					More data for this Ligand-Target Pair