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SMILES: COc1cc2c(Oc3ccc(NC(=O)c4nccc(n4)-c4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCN(C)CC1

InChI Key: InChIKey=YXNVRITWXLFAIM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50441415   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50441415
PNG
(CHEMBL2435961)
Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4nccc(n4)-c4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCN(C)CC1
Show InChI InChI=1S/C35H34F2N6O4/c1-42-15-17-43(18-16-42)14-3-19-46-33-22-29-26(21-32(33)45-2)30(11-13-38-29)47-31-9-8-25(20-27(31)37)40-35(44)34-39-12-10-28(41-34)23-4-6-24(36)7-5-23/h4-13,20-22H,3,14-19H2,1-2H3,(H,40,44)
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Similars
Article
PubMed
n/an/a 8n/an/an/an/an/an/a



Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL


Assay Description
Inhibition of c-MET (unknown origin) using poly (Glu, Tyr) (4:1) as substrate after 30 mins by spectrophotometric analysis

Eur J Med Chem 69: 77-89 (2013)


Article DOI: 10.1016/j.ejmech.2013.08.019
BindingDB Entry DOI: 10.7270/Q2BR8TKW
More data for this
Ligand-Target Pair