BDBM50441417 CHEMBL2435969

SMILES: COc1cc2c(Oc3ccc(NC(=O)c4cc(ccn4)-c4ccccc4)cc3F)ccnc2cc1OCCCN1CCCCC1

InChI Key: InChIKey=VGMYZLMRKMRCLC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50441417   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50441417 (CHEMBL2435969) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4cc(ccn4)-c4ccccc4)cc3F)ccnc2cc1OCCCN1CCCCC1 Show InChI InChI=1S/C36H35FN4O4/c1-43-34-23-28-30(24-35(34)44-20-8-19-41-17-6-3-7-18-41)38-16-14-32(28)45-33-12-11-27(22-29(33)37)40-36(42)31-21-26(13-15-39-31)25-9-4-2-5-10-25/h2,4-5,9-16,21-24H,3,6-8,17-20H2,1H3,(H,40,42)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.40	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-MET (unknown origin) using poly (Glu, Tyr) (4:1) as substrate after 30 mins by spectrophotometric analysis				Eur J Med Chem 69: 77-89 (2013) Article DOI: 10.1016/j.ejmech.2013.08.019 BindingDB Entry DOI: 10.7270/Q2BR8TKW
					More data for this Ligand-Target Pair