BDBM50441431 CHEMBL2436297

SMILES: Clc1ccc(Cn2c(CN3CCCC3)nc3ccccc23)c(Cl)c1

InChI Key: InChIKey=SIWZAVMOTHLEIC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50441431   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Heme Oxygenase 2 (HO-2) (Rattus norvegicus (rat))	BDBM50441431 (CHEMBL2436297) Show SMILES Clc1ccc(Cn2c(CN3CCCC3)nc3ccccc23)c(Cl)c1 Show InChI InChI=1S/C19H19Cl2N3/c20-15-8-7-14(16(21)11-15)12-24-18-6-2-1-5-17(18)22-19(24)13-23-9-3-4-10-23/h1-2,5-8,11H,3-4,9-10,12-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Queen's University Curated by ChEMBL					Assay Description Inhibition of HO-2 in Sprague-Dawley rat brain microsomal fractions assessed as carbon monoxide formation from methemalbumin after 10 mins by gas chr...				Bioorg Med Chem 21: 6788-95 (2013) Article DOI: 10.1016/j.bmc.2013.07.050 BindingDB Entry DOI: 10.7270/Q27082VV
					More data for this Ligand-Target Pair
Heme Oxygenase 1 (HO-1) (Rattus norvegicus (rat))	BDBM50441431 (CHEMBL2436297) Show SMILES Clc1ccc(Cn2c(CN3CCCC3)nc3ccccc23)c(Cl)c1 Show InChI InChI=1S/C19H19Cl2N3/c20-15-8-7-14(16(21)11-15)12-24-18-6-2-1-5-17(18)22-19(24)13-23-9-3-4-10-23/h1-2,5-8,11H,3-4,9-10,12-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Queen's University Curated by ChEMBL					Assay Description Inhibition of HO-1 in Sprague-Dawley rat spleen microsomal fractions assessed as carbon monoxide formation from methemalbumin after 10 mins by gas ch...				Bioorg Med Chem 21: 6788-95 (2013) Article DOI: 10.1016/j.bmc.2013.07.050 BindingDB Entry DOI: 10.7270/Q27082VV
					More data for this Ligand-Target Pair