BDBM50441484 CHEMBL2436587
SMILES: FC(F)(F)Oc1ccc(NC(=O)N2CCC3(C2)CCN(CC3)C(=O)C2CC2(F)F)cc1
InChI Key: InChIKey=AERCRGJRLDFMTN-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
EBifunctional epoxide hydrolase 2 (Homo sapiens (Human)) | BDBM50441484 (CHEMBL2436587) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant sEH using cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl]carbonate after 20 to 45 mins by ... | Bioorg Med Chem Lett 23: 5975-9 (2013) Article DOI: 10.1016/j.bmcl.2013.08.054 BindingDB Entry DOI: 10.7270/Q2TT4SDR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epoxide hydrolase 2 (Rattus norvegicus) | BDBM50441484 (CHEMBL2436587) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Toray Industries Inc. Curated by ChEMBL | Assay Description Inhibition of rat sEH expressed in Sf9 insect cells using cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl]carbonate after 2... | Bioorg Med Chem Lett 23: 5975-9 (2013) Article DOI: 10.1016/j.bmcl.2013.08.054 BindingDB Entry DOI: 10.7270/Q2TT4SDR | |||||||||||
More data for this Ligand-Target Pair |