BDBM50442182 CHEMBL2441828

SMILES: Cc1[nH]c2cn(-c3ccccc3)c(=O)c2c(c1CN)-c1ccc(Cl)cc1Cl

InChI Key: InChIKey=ZECFKNUFLJLNBY-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50442182   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 9 (Homo sapiens (Human))	BDBM50442182 (CHEMBL2441828) Show SMILES Cc1[nH]c2cn(-c3ccccc3)c(=O)c2c(c1CN)-c1ccc(Cl)cc1Cl |(9.71,-1.99,;8.38,-2.77,;7.04,-2.01,;5.71,-2.77,;4.24,-2.3,;3.34,-3.56,;1.8,-3.57,;1.02,-2.24,;-.53,-2.25,;-1.29,-3.58,;-.5,-4.92,;1.04,-4.9,;4.25,-4.81,;3.78,-6.27,;5.72,-4.32,;7.05,-5.09,;8.38,-4.32,;9.72,-5.09,;11.05,-4.31,;7.05,-6.63,;5.71,-7.39,;5.71,-8.93,;7.04,-9.7,;7.03,-11.24,;8.38,-8.93,;8.38,-7.4,;9.71,-6.62,)| Show InChI InChI=1S/C21H17Cl2N3O/c1-12-16(10-24)19(15-8-7-13(22)9-17(15)23)20-18(25-12)11-26(21(20)27)14-5-3-2-4-6-14/h2-9,11,25H,10,24H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of DPP9 (unknown origin)				J Med Chem 56: 7343-57 (2013) Article DOI: 10.1021/jm4008906 BindingDB Entry DOI: 10.7270/Q2N01806
					More data for this Ligand-Target Pair
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50442182 (CHEMBL2441828) Show SMILES Cc1[nH]c2cn(-c3ccccc3)c(=O)c2c(c1CN)-c1ccc(Cl)cc1Cl |(9.71,-1.99,;8.38,-2.77,;7.04,-2.01,;5.71,-2.77,;4.24,-2.3,;3.34,-3.56,;1.8,-3.57,;1.02,-2.24,;-.53,-2.25,;-1.29,-3.58,;-.5,-4.92,;1.04,-4.9,;4.25,-4.81,;3.78,-6.27,;5.72,-4.32,;7.05,-5.09,;8.38,-4.32,;9.72,-5.09,;11.05,-4.31,;7.05,-6.63,;5.71,-7.39,;5.71,-8.93,;7.04,-9.7,;7.03,-11.24,;8.38,-8.93,;8.38,-7.4,;9.71,-6.62,)| Show InChI InChI=1S/C21H17Cl2N3O/c1-12-16(10-24)19(15-8-7-13(22)9-17(15)23)20-18(25-12)11-26(21(20)27)14-5-3-2-4-6-14/h2-9,11,25H,10,24H2,1H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of DPP8 (unknown origin)				J Med Chem 56: 7343-57 (2013) Article DOI: 10.1021/jm4008906 BindingDB Entry DOI: 10.7270/Q2N01806
					More data for this Ligand-Target Pair