BDBM50442272 CHEMBL2442140

SMILES: CC(Sc1cc(cnc1N)-c1ccc(cc1)C(=O)N1CCN(C)CC1)c1c(Cl)ccc(F)c1Cl

InChI Key: InChIKey=ZLRHPCBASMAWBT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50442272   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50442272 (CHEMBL2442140) Show SMILES CC(Sc1cc(cnc1N)-c1ccc(cc1)C(=O)N1CCN(C)CC1)c1c(Cl)ccc(F)c1Cl Show InChI InChI=1S/C25H25Cl2FN4OS/c1-15(22-19(26)7-8-20(28)23(22)27)34-21-13-18(14-30-24(21)29)16-3-5-17(6-4-16)25(33)32-11-9-31(2)10-12-32/h3-8,13-15H,9-12H2,1-2H3,(H2,29,30)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISA				Bioorg Med Chem 21: 6804-20 (2013) Article DOI: 10.1016/j.bmc.2013.07.032 BindingDB Entry DOI: 10.7270/Q27P90TV
					More data for this Ligand-Target Pair