BDBM50442276 CHEMBL2442136

SMILES: CC(Sc1cc(cnc1N)-c1ccc(nc1)N1CCN(C)CC1)c1c(Cl)ccc(F)c1Cl

InChI Key: InChIKey=SXLSTGYKBDBRNB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50442276   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50442276 (CHEMBL2442136) Show SMILES CC(Sc1cc(cnc1N)-c1ccc(nc1)N1CCN(C)CC1)c1c(Cl)ccc(F)c1Cl Show InChI InChI=1S/C23H24Cl2FN5S/c1-14(21-17(24)4-5-18(26)22(21)25)32-19-11-16(13-29-23(19)27)15-3-6-20(28-12-15)31-9-7-30(2)8-10-31/h3-6,11-14H,7-10H2,1-2H3,(H2,27,29)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISA				Bioorg Med Chem 21: 6804-20 (2013) Article DOI: 10.1016/j.bmc.2013.07.032 BindingDB Entry DOI: 10.7270/Q27P90TV
					More data for this Ligand-Target Pair