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BDBM50442394 CHEMBL2442940

SMILES: CN(C(=O)Cn1c2cc(ccc2oc1=O)-c1cccnc1)c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=INPPXFAIFVJMMD-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50442394   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Translocator protein


(Homo sapiens (Human))		BDBM50442394
PNG
(CHEMBL2442940)
Show SMILES CN(C(=O)Cn1c2cc(ccc2oc1=O)-c1cccnc1)c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C22H16F3N3O3/c1-27(17-7-5-16(6-8-17)22(23,24)25)20(29)13-28-18-11-14(15-3-2-10-26-12-15)4-9-19(18)31-21(28)30/h2-12H,13H2,1H3
KEGG

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Similars
Article
PubMed
 8n/an/an/an/an/an/an/an/a



Dainippon Sumitomo Pharma Co., Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from TSPO in human U-87 MG cells after 1 hr by by liquid scintillation counting analysis

J Med Chem 56: 8191-5 (2013)


Article DOI: 10.1021/jm401325r
BindingDB Entry DOI: 10.7270/Q22Z1705
More data for this
Ligand-Target Pair