BDBM50442444 CHEMBL2443222

SMILES: Cc1cc(CCC(O)=O)cnc1CN1CCC2(CCN(C2=O)c2ccc(cc2)-c2ccccc2)CC1

InChI Key: InChIKey=AKSWRCRVZRGSKR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50442444   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Egl nine homolog 1 (Homo sapiens (Human))	BDBM50442444 (CHEMBL2443222) Show SMILES Cc1cc(CCC(O)=O)cnc1CN1CCC2(CCN(C2=O)c2ccc(cc2)-c2ccccc2)CC1 Show InChI InChI=1S/C30H33N3O3/c1-22-19-23(7-12-28(34)35)20-31-27(22)21-32-16-13-30(14-17-32)15-18-33(29(30)36)26-10-8-25(9-11-26)24-5-3-2-4-6-24/h2-6,8-11,19-20H,7,12-18,21H2,1H3,(H,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of PHD2 (unknown origin) by HTRF assay				Bioorg Med Chem 21: 6349-58 (2013) Article DOI: 10.1016/j.bmc.2013.08.046 BindingDB Entry DOI: 10.7270/Q2K075Q1
					More data for this Ligand-Target Pair