BDBM50442477 CHEMBL2440378

SMILES: COc1ccc2cc(Cc3cc(ccc3Cl)[C@@H]3O[C@H]([C@H](O)CO)[C@H](O)[C@H]3O)ccc2c1

InChI Key: InChIKey=XUYQOPLPMAPUTP-ZSXJVMONSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50442477   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50442477 (CHEMBL2440378) Show SMILES COc1ccc2cc(Cc3cc(ccc3Cl)[C@@H]3O[C@H]([C@H](O)CO)[C@H](O)[C@H]3O)ccc2c1 |r| Show InChI InChI=1S/C24H25ClO6/c1-30-18-6-4-14-8-13(2-3-15(14)11-18)9-17-10-16(5-7-19(17)25)23-21(28)22(29)24(31-23)20(27)12-26/h2-8,10-11,20-24,26-29H,9,12H2,1H3/t20-,21-,22-,23+,24-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as inhibition of [14C]-AMG uptake up to 120 mins by scintillation counting method				Bioorg Med Chem 21: 6282-91 (2013) Article DOI: 10.1016/j.bmc.2013.08.067 BindingDB Entry DOI: 10.7270/Q29G5P80
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (SGLT1) (Homo sapiens (Human))	BDBM50442477 (CHEMBL2440378) Show SMILES COc1ccc2cc(Cc3cc(ccc3Cl)[C@@H]3O[C@H]([C@H](O)CO)[C@H](O)[C@H]3O)ccc2c1 |r| Show InChI InChI=1S/C24H25ClO6/c1-30-18-6-4-14-8-13(2-3-15(14)11-18)9-17-10-16(5-7-19(17)25)23-21(28)22(29)24(31-23)20(27)12-26/h2-8,10-11,20-24,26-29H,9,12H2,1H3/t20-,21-,22-,23+,24-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of human SGLT1 expressed in CHO-K1 cells assessed as inhibition of [14C]-AMG uptake up to 120 mins by scintillation counting method				Bioorg Med Chem 21: 6282-91 (2013) Article DOI: 10.1016/j.bmc.2013.08.067 BindingDB Entry DOI: 10.7270/Q29G5P80
					More data for this Ligand-Target Pair