BDBM50442481 CHEMBL2440379

SMILES: OC[C@@H](O)[C@H]1O[C@H]([C@H](O)[C@H]1O)c1ccc(Cl)c(Cc2ccc3OCOc3c2)c1

InChI Key: InChIKey=WZGATMGZVPQHSV-MRBRGOBGSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50442481   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50442481 (CHEMBL2440379) Show SMILES OC[C@@H](O)[C@H]1O[C@H]([C@H](O)[C@H]1O)c1ccc(Cl)c(Cc2ccc3OCOc3c2)c1 |r| Show InChI InChI=1S/C20H21ClO7/c21-13-3-2-11(19-17(24)18(25)20(28-19)14(23)8-22)7-12(13)5-10-1-4-15-16(6-10)27-9-26-15/h1-4,6-7,14,17-20,22-25H,5,8-9H2/t14-,17-,18-,19+,20-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as inhibition of [14C]-AMG uptake up to 120 mins by scintillation counting method				Bioorg Med Chem 21: 6282-91 (2013) Article DOI: 10.1016/j.bmc.2013.08.067 BindingDB Entry DOI: 10.7270/Q29G5P80
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