BDBM50442484 CHEMBL2440373

SMILES: COc1ccccc1Cc1cc(ccc1Cl)[C@@H]1O[C@H]([C@H](O)CO)[C@H](O)[C@H]1O

InChI Key: InChIKey=GGUFSCVMWSNSBG-RACLHMPKSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50442484   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50442484 (CHEMBL2440373) Show SMILES COc1ccccc1Cc1cc(ccc1Cl)[C@@H]1O[C@H]([C@H](O)CO)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C20H23ClO6/c1-26-16-5-3-2-4-11(16)8-13-9-12(6-7-14(13)21)19-17(24)18(25)20(27-19)15(23)10-22/h2-7,9,15,17-20,22-25H,8,10H2,1H3/t15-,17-,18-,19+,20-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as inhibition of [14C]-AMG uptake up to 120 mins by scintillation counting method				Bioorg Med Chem 21: 6282-91 (2013) Article DOI: 10.1016/j.bmc.2013.08.067 BindingDB Entry DOI: 10.7270/Q29G5P80
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