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SMILES: COc1cccc(Cc2cc(ccc2Cl)[C@@H]2O[C@H]([C@H](O)CO)[C@H](O)[C@H]2O)c1

InChI Key: InChIKey=JTGQGCFLKZXMLJ-LTFPLMDUSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50442485   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium/glucose cotransporter 2


(Homo sapiens (Human))		BDBM50442485
PNG
(CHEMBL2440372)
Show SMILES COc1cccc(Cc2cc(ccc2Cl)[C@@H]2O[C@H]([C@H](O)CO)[C@H](O)[C@H]2O)c1 |r|
Show InChI InChI=1S/C20H23ClO6/c1-26-14-4-2-3-11(8-14)7-13-9-12(5-6-15(13)21)19-17(24)18(25)20(27-19)16(23)10-22/h2-6,8-9,16-20,22-25H,7,10H2,1H3/t16-,17-,18-,19+,20-/m1/s1
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Similars
Article
PubMed
n/an/an/an/a>5.00E+4n/an/an/an/a



National Taiwan University

Curated by ChEMBL


Assay Description
Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as inhibition of [14C]-AMG uptake up to 120 mins by scintillation counting method

Bioorg Med Chem 21: 6282-91 (2013)


Article DOI: 10.1016/j.bmc.2013.08.067
BindingDB Entry DOI: 10.7270/Q29G5P80
More data for this
Ligand-Target Pair